Anti ATM(R2443Q) Mouse Monoclonal Antibody

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Anti ATM(R2443Q) Mouse Monoclonal Antibody

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武汉纽斯特生物科技有限公司

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武汉纽斯特生物科技有限公司(Wuhan NewEast Biotechonology Co.Ltd),系美国生命科学试剂供应商美国NewEastBio在中国的子公司。公司位于武汉东湖*开发区光谷生物城. 美国NewEastBio专注于生命科学和生物技术领域,主要产品有抗体、小分子、ELISA试剂盒、蛋白等,与世界许多高校和研究所、世界大制药公司、生物科技公司和医院等客户建立了*稳定的合作关系,产品销往各个国家。 武汉纽斯特生物将携手美国NewEastBio,负责美国品牌NewEastBio(www.neweastbio.com)产品在中国市场的推广、销售及售后服务。致力于为客户提供一系列高质量和有较好价格竞争力的美国NewEastBio*产品。并提供专业的技术服务:抗体定制,动物实验等

详细信息

ATM(R2443Q) [26143]
[100 µL]


Catalog Number:  26143
Gene Symbol:  ATM
Description:   Anti ATM(R2443Q) Mouse Monoclonal Antibody
Background:   Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activity of ATM protein is under tight control, and mutation of ATM can cause disease such as Ataxia telangiectasia (AT) and cancers.
Immunogen:    A synthetic peptide from the internal region of ATM which includes the mutation of R2443Q, human origin.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:5000 
WB: 1:100-1:1000 
IHC: 1:50-1:100
Concentration:   1 mg/ml
Host:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes ATM(R2443Q), but not wild type ATM protein from vertebrates.
Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles
Download Datasheet:  
Western blot:  
Western blot analysis of recombinant ATM(R2443Q) and wildtype proteins. Purified His-tagged ATM(R2443Q) protein (amino acids 2400-3056, lane 2) and corresponding wild type protein (lane 1) were blotted with Anti ATM(R2443Q) mouse monoclonal antibody (Cat. #26143).


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