产品名称：anti-mouse CD86 FITC GL1 50 ug
货号：eBioscience 11-0862-81
规格：50 ug
产品说明：
Anti-Mouse CD86 （B7-2） FITC
Also known as: B7.2, B70, Ly-58
Description: The GL1 monoclonal antibody reacts with mouse CD86, an ~80 kDa surface receptor also known as B7-2. CD86 & CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed at low level on B cells, macrophages, and dendritic cells and is upregulated on B cells through a variety of surface stimuli including the BCR complex, CD40 and some cytokine receptors. CD86 is also expressed by activated mouse T cells and thioglycolate-elicited peritoneal cells. In addition to CD80 （B7-1）, CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 （CTLA-4）. This interaction plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation, supports its major contribution during the primary phase of an immune response.