上海力敏实业有限公司

中级会员第13年

代理商

进入商铺全部产品

该企业相似产品

miltenyi美天旎MACS Supplement B27 PLUS（NeuroBrew-21）

在线询价

FGF-4人细胞生长因子Recombinant Human FGF-4

在线询价

Peprotech重组人TGF-β1细胞因子Recombinant Human TGF-β1 （mammalian derived）

在线询价

R&D Recombinant Human/mouse IL-17A重组人/小鼠白介17细胞因子

在线询价

R&D供应商Recombinant Rat FGF basic 重组大鼠碱性成纤维细胞生长因子

在线询价

R&D代理Recombinant Rat EGF重组鼠表皮生长因子RD供应*

在线询价

M-CSF的重组小鼠细胞因子Recombinant Mouse M-CSF

在线询价

RD Recombinant human IL-17A人白介17因子

在线询价

主营产品公司介绍

生化试剂,抗体，氨基酸，实验耗材，小型仪器设备等

上海力敏实业有限公司，是一家专注于生命科学和生物技术领域的企业，主要从事分子生物学、细胞生物学、免疫学、蛋白组学等实验研究的相关试剂、耗材及仪器的销售，汽车发动机行业清洁度检测，大气环境监测仪器耗材，食品安全检测，水质监测与质控等。致力于在各个领域内向用户提供世界水平和质量稳定的产品，同时也为客户提供相关的实验服务。公司主要代理 Abcam、R&D、Sigma、NALGENE、WHATMAN、Millipore、Pall等，和供应商有着良好的合作关系，同时致力于不断完善自身的供应体系，以便能更好的服务于国内的广大客户和企业。

详细信息

Recombinant Human HGF

Catalog Number:

100-39

Synonyms:

Scatter Factor （SF）, Hepatopoietin （HPTA）

Description:

HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains （α-chain and β-chain） held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 234 amino acid residues.*Manufactured using （BTI-Tn-5B1-4） cells under license from Boyce Thompson Institute for Plant Research, Inc.

AA Sequence:

alpha chain: QRKRRNTIHE FKKSAKTTLI KIDPALKIKT KKVNTADQCA NRCTRNKGLP FTCKAFVFDK ARKQCLWFPF NSMSSGVKKE FGHEFDLYEN KDYIRNCIIG KGRSYKGTVS ITKSGIKCQP WSSMIPHEHS FLPSSYRGKD LQENYCRNPR GEEGGPWCFT SNPEVRYEVC DIPQCSEVEC MTCNGESYRG LMDHTESGKI CQRWDHQTPH RHKFLPERYP DKGFDDNYCR NPDGQPRPWC YTLDPHTRWE YCAIKTCADN TMNDTDVPLE TTECIQGQGE GYRGTVNTIW NGIPCQRWDS QYPHEHDMTP ENFKCKDLRE NYCRNPDGSE SPWCFTTDPN IRVGYCSQIP NCDMSHGQDC YRGNGKNYMG NLSQTRSGLT CSMWDKNMED LHRHIFWEPD ASKLNENYCR NPDDDAHGPW CYTGNPLIPW DYCPISRCEG DTTPTIVNLD HPVISCAKTK QLR

beta chain: VVNGIP TRTNIGWMVS LRYRNKHICG GSLIKESWVL TARQCFPSRD LKDYEAWLGI HDVHGRGDEK CKQVLNVSQL VYGPEGSDLV LMKLARPAVL DDFVSTIDLP NYGCTIPEKT SCSVYGWGYT GLINYDGLLR VAHLYIMGNE KCSQHHRGKV TLNESEICAG AEKIGSGPCE GDYGGPLVCE QHKMRMVLGV IVPGRGCAIP NRPGIFVRVA YYAKWIHKII LTYKVPQS

Source:

（BTI‐Tn‐5B1‐4） Hi‐5 Insect cells*

Purity:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of monkey 4MBr-5 cells was found to be in the range of 20.0-40.0 ng/ml.

Cross Reactivity:

Dog, Monkey, Mouse, Rabbit, Rat, Human + Mouse, Human, Leech

Research Interests: