- 面议
起订量：
FITC标记的芳香乙酰胺脱乙酰基酶抗体
- 型号
该企业相似产品
南京森贝伽生物科技有限公司，http://www.senbeijia.com/（NanJing SenBeiJia Biotechnology Co.,LTD.）成立于2012年，位于江宁大学城，是一家立足于生命科学领域有自主知识产权的国家*，公司现有员工40余人，产品涵盖分子生物学、蛋白质组学、免疫学、细胞生物学等研究和应用领域。
主营产品：
拥有发明的自主研发ELISA试剂盒，经验丰富，质量过硬。
经营免疫学、蛋白质学、分子生物学、细胞生物学方面的抗体、血清、试剂、试剂盒及相关实验耗材，自制标准品，中检所断货标准品。
经销品牌：
Abcam、Anaspec、CST、BD Pharmingen、Santa Cruz、Jackson、R&D、Merck Millipore、gibco、
hyclone、Amresco、Bio-World、Bio-Rad、Life、MACS、MACS、NEB、Novus、Sigma、Tocris、Corning、Axygen、Takara(未提及的品牌，我公司可以代购)
实验代做服务：
公司拥有*的仪器设备和一批海归博士、硕士研究人员，并在清华大学建有自己的实验室与研发基地，为生命科学客户提供实验技术服务，如酶联免疫ELISA、Western Blot、免疫组化（包埋，切片，HE）、Realtime PCR、流式细胞检测等。
企业宗旨是：提供*质的产品和服务，做有影响力的生物技术公司
在21世纪生命科学迅猛发展的时代，南京森贝伽生物科技有限公司在我们全体员工的不懈努力下，以Z快速、Z高质量、较好的态度，为客户提供一个稳定平台，为客户提供优质的服务，成为客户可信赖的*合作的伙伴，相信在未来的工作中，南京森贝伽一定能够成为您得力的助手和值得信赖的合作伙伴！
详细信息
FITC标记的芳香乙酰胺脱乙酰基酶抗体是我司为您提供的高品质抗体，公司生产的每一个抗体都经过严格检测和稳定性测试，保证了结果的准确性、敏感性、特异性。公司产品质量有保证，*且我司拥有完善的市场营销体系、现代化管理体系和专业化物流配送系统，zui大程度满足国内外生命科研人员的产品需求，公司现经营抗体、ELISA试剂盒、标准品、染色液、染色试剂盒、培养基等多种科研产品，欢迎前来选购！
英文名称 Anti-AADAC/FITC
中文名称 FITC标记的芳香乙酰胺脱乙酰基酶抗体
别 名 AAAD_HUMAN; Aada; Aadac; Arylacetamide deacetylase (esterase); Arylacetamide deacetylase; CES5A1; DAC.
说 明 书 100ug
研究领域 肿瘤 细胞生物 信号转导
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
产品应用 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AADAC (228-273aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The assembly of very-low-density lipoproteins (VLDLs) in the secretory apparatus of the hepatocyte relies on the mobilization of triacylglycerol (TAG) from the cytosolic pool by lipolysis and re-esterification. However, some of the re-esterified TAG products are returned to the cytosolic pool in the liver, which protects vulnerable body tissues from excess lipotoxic non-esterified fatty acids in the plasma. Some of the lipases involved in this process include arylacetamide deacetylase (AADAC) and its related proteins AADACL1 and AADACL2. AADAC, a single pass type II membrane protein of the endoplasmic reticulum, is expressed in hepatocytes, intestinal mucosal cells, pancreas and adrenal gland. It plays an important role in the metabolic activation of arylamine substrates to ultimate carcinogens. AADACL1 hydrolyzes the metabolic intermediate 2-acetyl monoalkylglycerol, and its inactivation results in disruption of ether lipid metabolism in cancer cells and impaired cell migration and tumor growth.
Function:
Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionaly causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.
Subcellular Location:
Endoplasmic reticulum membrane. Microsome membrane.
Tissue Specificity:
Mainly expressed in liver, small intestine, colon and adrenal gland.
Similarity:
Belongs to the 'GDXG' lipolytic enzyme family.
Database links:
UniProtKB/Swiss-Prot: P22760.5
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
