小鼠抗鸡IgY抗体

小鼠抗鸡IgY抗体

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2015-06-17 10:07:20
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江苏宝莱生物科技有限公司

江苏宝莱生物科技有限公司

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产品简介

小鼠抗鸡IgY抗体产品介绍:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

详细介绍

英文名称chicken IgY
中文名称小鼠抗鸡IgY抗体
别    名Egg yolk immunoglobulin; IgY.
说 明 书1mg  10mg  
抗体来源Mouse
克隆类型Polyclonal
交叉反应Chicken, 
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量180kDa
性    状Lyophilized or Liquid
浓    度1mg/1ml
免 疫 原chicken IgY
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M PBS, pH 7.4
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
In chickens, immunoglobulin Y is the functional equivalent to Immunoglobulin G (IgG). Like IgG, it is composed of two light and two heavy chains. Structurally, these two types of immunoglobulin differ primarily in the heavy chains, which in IgY have a molecular mass of about 65,100 atomic mass units (amu), and are thus larger than in IgG. The light chains in IgY, with a molar mass of about 18,700 amu, are somewhat smaller than the light chains in IgG. The molar mass of IgY thus amounts to about 167,000 amu. The steric flexibility of the IgY molecule is less than that of IgG.Functionally, IgY is partially comparable to Immunoglobulin E (IgE), as well as to IgG. However, in contrast to IgG, IgY does not bind to Protein A, to Protein G, or to cellular Fc receptors. Furthermore, IgY does not activate the complement system. The name Immunoglobulin Y was suggested in 1969 by G.A. Leslie and L.W. Clem, after they were able to show differences between the immunoglobulins found in chicken eggs, and immunoglobulin G. Other synonymous names are Chicken IgG, Egg Yolk IgG, and 7S-IgG.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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