mouse Anti-CA125 说明
时间:2014-05-11 阅读:489
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提供商
上海瑞齐生物科技有限公司 -
资料大小
22525 -
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下载次数
98次 -
资料类型
gif -
浏览次数
489次
时间:2014-05-11 阅读:489
提供商
上海瑞齐生物科技有限公司资料大小
22525资料图片
点击查看下载次数
98次资料类型
gif浏览次数
489次mouse Anti-CA125
From:abcam
Catalog Number : RS-0091R
Quantity size : 100ul (dilute with pH 7.4 0.01 M PBS or antibody diluent )
background:
MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is overexpressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators.
Function:
Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Subunit:
Binds to MSLN. Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.
Specificity : Anti-CA125 is a mouse monoclonal antibody
specific for anti-CA125 of Rat ,human,mouse,
- use for western blotting,elisa,immunoprecipitation and immunohistochemistry
Application :
KLH conjugated synthetic peptide derived from human CA125
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.