Stemolecule™ CHIR99021（GSK-3β抑制剂）

产品关键词：

GSK-3β；naïve stem cells 初始干细胞；neural progenitor cells 神经祖细胞；WH-4-023；Y27632；PD0325901；CAS：252917-06-9；

产品描述：

氨基嘧啶CHIR99021是目前为止报道的选择性zui强的GSK-3β抑制剂。与其他强效的GSK-3抑制剂相比，CHIR99021不会交叉抑制细胞周期蛋白依赖性激酶（CDKs），对GSK-3β的选择性是对CDKs的350倍。与抑制MAPK来源的分化诱导信号联合，使用CHIR99021阻断 GSK-3β信号使得胚胎干细胞能自我更新。

产品特性

1. 同义名：6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2 pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile

2. 分子式：C₂₂H₁₈Cl₂N₈

3. 分子量：465.34 g/mol

4. CAS NO：252917-06-9

5. 纯度：＞95%（HPLC）

6. 外观：Off-white solid

7. 溶解性：DMSO

8. 保存和稳定性：粉末4 °C避光保存，重溶后的储存液分装后-20 °C保存，6个月稳定。

9. 质量控制：HPLC测定纯度，MS测定准确分子量，CHIR99021对小鼠胚胎干细胞的细胞毒性测试。

10. 结构图：

订购信息：原装好货，欢迎订购，：，：。

引用文献：

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— —Written/Edited by V. Shallan【版权归MKBio懋康所有】

上海懋康生物科技有限公司是一家涉足于生命科学和生物技术领域研究的试剂、仪器和实验室消耗品与实验服务工作，主要从事细胞生物学、植物学、分子生物学、免疫学、生物化学、蛋白组学。生物制药与诊断试剂研发生产等领域。 本公司秉承“以人为本，以诚为信、合同守信”的经营理念。坚持"品质保障"的原则为广大客户提供优质产品。

Stemolecule™ CHIR99021（GSK-3β抑制剂）

Stemolecule™ CHIR99021（GSK-3β抑制剂）

Stemolecule™ CHIR99021（GSK-3β抑制剂）