品牌
生产厂家厂商性质
上海市所在地
分类 抗体
含量 ≥97 (SDS-PAGE)(%)
产品规格 SIGMA E9644-0.2MG
CAS 62253-63-8
品牌 SIGMA
用途范围 生物科研
保存温度 -20℃
英文名称 Epidermal Growth Factor human-EGF human
供应商 上海研伴实业有限公司
recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
· 产品编号:E9644
· 中文名称:表皮生长因子 人类
· 英文名称:Epidermal Growth Factor human-EGF human
· 英文别名:EGF LONG® EGF
· CAS号:62253-63-8
· 纯度:≥97% (SDS-PAGE)
· 保存温度:−20 °C
· MDL号:MFCD00132565
产品规格价格(RMB)
· E9644-0.2MG2,999.88元
· E9644-5X0.2MG13,209.30元
Analysis Note
≥98% SDS-PAGE
Biochem/physiol Actions
Qualified for use as a mitogen for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline
Application
Qualified for use as a mitogen for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.
General description
Epidermal Growth Factor (EGF) is a small mitogenic polypeptide which is present in many mammalian species and is distributed throughout a wide number of tissues and body fluids. Human EGF is identical to β-urogastrone, a polypeptide which was recognized and isolated on the basis of its ability to inhibit gastric acid secretion. EGF is a member of a growth factor family which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF. EGF is structurally homologous to human transforming growth factor-α (TGF-alpha), and both exert their actions through EGF receptors. EGF is homologous to a sequence contained in a 19 kD protein of vaccinia virus, which appears to utilize the EGF receptor to gain entry into cells.
EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.
法律信息
LONG 注册商标 Novozymes Gropep Limited
Other Notes
The biological activity of recombinant, human EGF is measured by its ability to stimulate the mouse fibroblast cell line, BALB/3T3. The EC50 is defined as the effective concentration of growth factor that elicits a 50% increase in cell growth in a cell based bioassay.
Related Categories | Cancer Research Cell Biology Cell Culture Cell Culture Supplies Cell Signaling and Neuroscience更多... |
Quality Level | PREMIUM |
recombinant | expressed in E. coli |
assay | ≥97% (SDS-PAGE) |
form | lyophilized powder |
potency | 0.08-0.8 ng/mL ED50/EC50 |
total impurities | ≤1 EU/μg endotoxin(EGF) |
suitability | suitable for cell culture |
storage temp. | −20°C |
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