5-氮杂-2-脱氧胞苷，SIGMA A3656-5mg

分类 其他生化试剂

级别 优级纯GR

含量 ≥97（％）

产品规格 SIGMA A3656-5MG

CAS  2353-33-5

品牌 Sigma

用途范围 生物科研

保存温度 常温

分子式 C8H12N4O4

分子量 228.21

供应商  上海研伴实业有限公司

5-氮杂-2-脱氧胞苷           SIGMA A3656-5MG

≥97%

· 产品编号：A3656

· 中文名称：5 - 氮杂-2-脱氧胞苷

· 英文名称：5-Aza-2-deoxycytidine

· CAS号：2353-33-5

· 分子式：C8H12N4O4

· 分子量：228.21

· 纯度：≥97%

· 保存温度：常温

订货信息：

产品规格价格(RMB)

· A3656-5MG    电仪/元

· A3656-10MG    电仪/元

· A3656-50MG    电仪/元

注：此价格仅供参考，请以SIGMA价格为准，优惠价请电询。

性能描述

General description

Decitabine is an epigenetic modifier that inhibits DNA methyltransferase activity which results in DNA demethylation (hypomethylation) and gene activation by remodeling opening chromatin. Genes are synergistically reactivated when demethylation is combined with histone hyperacetylation.

Biochem/physiol Actions

5′-Azadeoxycytidine causes DNA demethylation or hemi-demethylation. DNA demethylation can regulate gene expression by opening the chromatin structure detectable as increased nuclease sensitivity. This remodeling of chromatin structure allows transcription factors to bind to the promoter regions, assembly of the transcription complex, and gene expression.

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