英文名称：BCHE；BuCHE ；Cholinesterase,butyryl（Horse serum） ；Acylcholine acyl-hydrolase；Choline esterase, butyryl；Pseudocholinesterase
CAS号：9001-08-5

分子量：～440000

级别：BR
活力：≥4units/mg

产品描述：It catalyzes the hydrolysis of a number of choline esters according to the following reaction：Acylcholine+H2O to choline+acid.It is a tetrameric glycoprotein with four subunits of equal size,each having a molecular weight of 110KDa.Butyryl cholinesterase hydrolyzes butyrylcholine four times more rapidly than acetylcholine.It is inhibited by 10-5 M physostigmine，numerous organophosphate esters,the carbamate derivates and quaternary ammonium saltsunit hydrolyzes 1umole of acetylchoine per minute at 25℃, pH7.4
性状：淡褐色粉末。*酯酶有2种：AChE和丁酰*酯酶（BuChE）。两者的基因结构、氨基酸序列及空间三维结构均显示了很高的同源性。二者的主要差异在于，AChE水解乙酰*（ACh）和乙酰硫代*（ATCh）比丙酰*（PrCh）快，对丁酰*（BuCh）和丁酰硫代*（BuTCh）没有明显的水解作用。丁酰*酯酶与乙酰*酯酶的显色反应原理是*一样的。丁酰*酯酶具有灵敏度更高的优点
用途：生化研究。是一类糖蛋白，水解乙酸*。是生物神经传导中的一种关键性酶，同时又是有机磷和氨基甲酸酯杀虫剂的靶标。保存：2～8℃