P4SPR凭借紧凑的设计，您可以通过减少样品制备时间和在工作台或现场使用SPR来更快地进行分析测试。我们的技术不仅可以检测和监测生物分子，如多肽、蛋白、核酸等各种生物分子的相互作用，还可以测量结合动力学，且设备方便携带，还可以用于户外现场中的农药残留、微量药物、污染物等环境检测。

关于Affinité Instruments公司

*Affinité Instruments 2015年由加拿大蒙特利尔大学教授Jean-François Masson创办

*基于Jean-François Masson教授十数年在SPR领域积累的深厚经验， Affinité Instruments 成功开发并商业化基于  SPR原理的新一代非标记分子相互作用分析仪P4SPR，助力基础研究

-基于SPR原理， 实时、 无标记、检测相互作用

-适用于小分子化合物、核酸、多肽、蛋白、抗体、脂类、多糖、纳米颗粒、病毒、微生物、细胞等各种类型样品

-10分钟内完成测试，获得特异性、亲和力、动力学、浓度等数据

-可检测各种在复杂溶液之中完成测量，比如血液、牛奶、细胞裂解液等
-4通道同时检测，实时扣除背景，获得可信数据
-可手动进样或者进样泵，操作简单，无需维护
-可与其它仪器（ HPLC,MS等）联合使用
-价格适中，单个实验室即可负担
-仪器小巧， 易于携带
-仪器稳定、可用于户外环境现场检测

* Title Journal Journal details Year Area Document Column Hybridization conditions of oligonucleotidecapped gold nanoparticles for SPR sensing of
microRNA. Biosensors and Bioelectronics, 2018 Volume 109, Pages 230Z236
* Tracking silent hypersensitivity reactions to asparaginase during leukemia therapy using single-chip indirect plasmonic and fluorescence
immunosensing. ACS Sensors. 2017 2A12B{1761Z1766.
* Gomez-Diaz C, Bargeton B, Abuin L, Bukar N, Reina JH, Bartoi T, Graf M, Ong H, Ulbrich MH, Masson JF, Benton R. A CD36 ectodomain mediates
insect pheromone detection via a putative tunnelling mechanism. Nat Commun. 2016 Jun 15;7:11866.
* Chehboun S, Labrecque-Carbonneau J, Pasquin S, Meliani Y, Meddah B, Ferlin W, Sharma M, Tormo A, Masson JF, Gauchat JF. Epstein-Barr virusinduced gene 3 (EBI3) can mediate IL-6 trans-signaling. J Biol Chem. 2017 Apr 21;292(16):6644-6656.
* Brulé T, Granger G, Bukar N, Deschênes-Rancourt C, Havard T, Schmitzer AR, Martel R, Masson JF. A field-deployed surface plasmon resonance
(SPR) sensor for RDX quantification in environmental waters. Analyst. 2017 Jun 21;142(12):2161-2168.
* Aubé A, Campbell S, Schmitzer AR, Claing A, Masson JF. Correction: Ultra-low fouling alkylimidazolium modified surfaces for the detection of HER2
in breast cancer cell lysates. Analyst. 2017 Aug 7;142(16):3011.
* Charbonneau DM, Aubé A, Rachel NM, Guerrero V, Delorme K, Breault-Turcot J, Masson JF, Pelletier JN. Development of Escherichia coli
Asparaginase II for Immunosensing: A Trade-Off between Receptor Density and Sensing Efficiency. ACS Omega. 2017 May 31;2(5):2114-2125.
* McKeating KS, Aubé A, Masson JF. Biosensors and nano biosensors for therapeutic drug and response monitoring. Analyst. 2016 Jan
21;141(2):429-49.
* Yockell-Lelièvre H, Bukar N, McKeating KS, Arnaud M, Cosin P, Guo Y, Dupret-Carruel J, Mougin B, Masson JF. Plasmonic sensors for the
competitive detection of testosterone. Analyst. 2015 Aug 7;140(15):5105-11.
* Zhao SS, Bukar N, Toulouse JL, Pelechacz D, Robitaille R, Pelletier JN, Masson JF. Miniature multi-channel SPR instrument for methotrexate
monitoring in clinical samples. Biosens Bioelectron. 2015 Feb 15;64:664-70.
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