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Human ALKBH2,重组人ALK 烷基化修复同系物2
面议
Human ALDOC,重组人果糖二磷酸醛缩酶A
面议
Human ALDOA,重组人醛缩酶A
面议
Human ALDH5A1,重组人醛脱氢酶3A1
面议
Human ALDH3A1,重组人醛脱氢酶3A1
面议
Human ALDH2,重组人醛脱氢酶2
面议
Human ALDH1A1,重组人醛脱氢酶1A1
面议
Human ALAT,重组人*转氨酶
面议
Human AKR7A3,重组人醛酮还原酶7-A3
面议
Human AKR7A2,重组人醛酮还原酶7-A2
面议
Human AKR1D1,重组人醛酮还原酶1-D1
面议
Human AKR1C4,重组人醛酮还原酶1-C4
面议| Catalogue Number | CYT-691 | ||||||
| Synonyms | GDF-15, MIC1, MIC-1, NAG-1, PDF, PLAB, PTGFB, Growth/differentiation factor 15, Placental bone morphogenetic protein, Placental TGF-beta, Macrophage inhibitory cytokine 1, Prostate differentiation factor, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, NRG-1, GDF15. | ||||||
| Introduction | GDF15 is part of the TGF-Beta superfamily that is involved in regulating inflammatory and apoptotic pathways in injured tissues and throughout disease processes. GDF15 is most abundant in the liver. Its expression in liver can be considerably up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF-15 promotes proliferation or growth arrest and differentiation due to differences in cellular differentiation. GDF15 prevents apoptosis in cerebellar granule neurons by activating Akt and inhibiting endogenously active ERK. GDF15 is a novel autocrine/endocrine factor that antagonizes the hypertrophic response and loss of ventricular performance. | ||||||
| Description | Recombinant Human GDF15 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 151 amino acids （195-308） and having a molecular mass of 16.7 kDa（molecular weight on SDS-PAGE will appear higher）. GDF15 is expressed with a 36 amino acid His tag fused at N-Terminus and purified by proprietary chromatographic techniques. | ||||||
| Source | Escherichia Coli. | ||||||
| Physical Appearance | Sterile filtered colorless solution. | ||||||
| Formulation | The GDF15 protein solution contains 10mM sodium citrate, pH-3.5 & 10% glycerol. | ||||||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. | ||||||
| Purity | Greater than 95.0% as determined by SDS-PAGE. | ||||||
| Amino Acid Sequence | MRGSHHHHHH GMASMTGG MGRDLYDDDD KDRWGSMARA RNGDHCPLGP GRCCRLHTVR ASLEDLGWAD WVLSPREVQV TMCIGACPSQ FRAANMHAQI KTSLHRLKPD TVPAPCCVPA SYNPMVLIQK TDTGVSLQTY DDLLAKDCHC I. | ||||||
| Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | ||||||
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