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Human ALKBH2,重组人ALK 烷基化修复同系物2
面议Human ALDOC,重组人果糖二磷酸醛缩酶A
面议Human ALDOA,重组人醛缩酶A
面议Human ALDH5A1,重组人醛脱氢酶3A1
面议Human ALDH3A1,重组人醛脱氢酶3A1
面议Human ALDH2,重组人醛脱氢酶2
面议Human ALDH1A1,重组人醛脱氢酶1A1
面议Human ALAT,重组人*转氨酶
面议Human AKR7A3,重组人醛酮还原酶7-A3
面议Human AKR7A2,重组人醛酮还原酶7-A2
面议Human AKR1D1,重组人醛酮还原酶1-D1
面议Human AKR1C4,重组人醛酮还原酶1-C4
面议Synonyms | ADK2, AK-2, Adenylate kinase isoenzyme 2 mitochondrial, ATP-AMP transphosphorylase 2, adenylate kinase 2. | |||
Introduction | Adenylate kinases play a role in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. There are 3 types of adenylate kinase isozymes, AK1, AK2, and AK3 in vertebrates. Expression of these isozymes are tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and is involved in apoptosis. AK2 is mutated in individuals with reticular dysgenesis. | |||
Description | AK2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 259 amino acids and having a molecular mass of 28.6 kDa. AK2 is fused to 20 a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques. | |||
Source | Escherichia Coli. | |||
Physical Appearance | Sterile filtered colorless solution. | |||
Formulation | AK2 solution containing 20mM Tris pH-7.5, 5mM DTT and 20% glycerol. | |||
Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MAPSVPAAEP EYPKGIRAVL LGPPGAGKGTQAPRLAENFC VCHLATGDML RAMVASGSEL GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM LDDLMEKRKE KLDSVIEFSIPDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNE KALKIRLQAY HTQTTPLIEY YRKRGIHSAI DASQTPDVVF ASILAAFSKA TCKDLVMFI. | |||
Stability | AK2 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |||
Purity | Greater than 95.0% as determined by SDS-PAGE. | |||
Biological Activity | Specific activity: > 1.5 units/ml. One unit will convert 2.0 umoles of ADP to ATP + AMP per minute at pH 7.5 at 25C. | |||
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | |||
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